July 2023 // Communication
Synendos Therapeutics AG announces that co-founder and Scientific Advisor Board member, Professor Jürg Gertsch, presented groundbreaking...
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FOUNDING TEAM
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FOUNDING TEAM
Lorem ipsum dolor sit amet, consectetur adipiscing elit. Quisque leo mauris, pretium et ipsum quis, convallis ullamcorper sem. Maecenas elementum nibh nisi, eu auctor nunc pulvinar vitae. Donec ut interdum leo. Nam ac felis semper, facilisis nulla venenatis, molestie nibh.
FOUNDING TEAM
Lorem ipsum dolor sit amet, consectetur adipiscing elit. Quisque leo mauris, pretium et ipsum quis, convallis ullamcorper sem. Maecenas elementum nibh nisi, eu auctor nunc pulvinar vitae. Donec ut interdum leo. Nam ac felis semper, facilisis nulla venenatis, molestie nibh.
FOUNDING TEAM
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PD Dr. Andrea Chicca
Project leader/senior scientist at UniBern.
2 years in pharma industry.
8 years of research activity on the ECS
Prof. Dr. Jürg Gertsch
Full Professor at UniBern.
Collaboration with pharma industry.
10+ years of research activity on the ECS.
Synendos Therapeutics
First-in-class endocannabinoid modulators to restore natural functioning of the brain in CNS disorders.
OUR ACTIVITY
Synendos Therapeutics is a biopharmaceutical company that aims to develop breakthrough safe and effective therapies for unmet needs in neuropsychiatric disorders through modulation of a new drug target in the endocannabinoid system that enables restoration of natural functioning of the brain.
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Our mission is to advance the preclinical and clinical development of a new class of small molecules that act as selective endocannabinoid reuptake inhibitors (SERIs).
SERIs are competitive and reversible first-in-class inhibitors that restore the normal functioning of the endocannabinoid system by increasing the levels of endogenous cannabinoids (endocannabinoids) and represent an innovative therapeutic approach for central nervous system (CNS) disorders.
Our lead programme is focused on high unmet medical needs in the area of anxiety, mood and stress-related disorders. Synendos was founded as a University of Bern and NCCR TransCure spin-off in April 2019. Synendos arises from many years of solid basic research on endocannabinoid biology and pharmacology and a thorough medicinal chemistry programme that led to identification of our preclinical drug candidate SYT-510.
INNOVATIVE APPROACH TO PROVIDE MORE SAFE AND EFFECTIVE THERAPIES FOR CNS DISORDERS
The endocannabinoid system is a key neuromodulator system in the CNS and represents a promising therapeutic target for a wide range of CNS diseases characterized by insufficient endocannabinoid signalling (deficiency).
Selective endocannabinoid reuptake inhibitors (SERIs) can restore normal endocannabinoid tone through the modulation of a newly identified drug target responsible of endocannabinoid cell reuptake.
SERIs can exert pro-homeostatic effects on different neuronal circuits by acting with a self-limiting mechanism of action. At Synendos, we advance the preclinical and clinical development of SYT-510 and two other possible follow up compounds.
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